4-Pyridinecarbothioamide → HCID 22049802, 화합물

반응식

Br[CH2:2][C:3]([C:5]1[CH:6]=[N:7][CH:8]=[CH:9][C:10]=1[CH3:11])=O.[C:12]([NH2:20])(=[S:19])[C:13]1[CH:18]=[CH:17][N:16]=[CH:15][CH:14]=1>>[CH3:11][C:10]1[CH:9]=[CH:8][N:7]=[CH:6][C:5]=1[C:3]1[N:20]=[C:12]([C:13]2[CH:18]=[CH:17][N:16]=[CH:15][CH:14]=2)[S:19][CH:2]=1

참가 물질

반응물 2

HCID 27237884-Pyridinecarbothioamide

HCID 220497832-Bromo-1-(4-methylpyridin-3-yl)ethan-1-one

생성물 1

HCID 22049802HCID 22049802, 화합물수율 27.5%

실험 절차

By the reaction in the same manner as in Example 25-iii) using 2-bromo-1-(4-methylpyridin-3-yl)ethanone hydrobromate (428 mg) and thioisonicotinamide (153 mg), the title compound (77 mg) was obtained as colorless powder crystals.

후처리

customBy the reaction in the same manner as in Example 25-iii)

출처 및 근거

ORD 기록: ord-505e4386fb5c46aeaba5b5a6854d97d2
출처 데이터셋: uspto-grants-2006_06
DOI: 10.6084/m9.figshare.5104873.v1
특허 번호: US07067537B2

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