5-Bromo-N-ethylpyridine-3-carboxamide → HCID 22049754, 화합물

반응식

Br[C:2]1[CH:3]=[N:4][CH:5]=[C:6]([CH:12]=1)[C:7]([NH:9][CH2:10][CH3:11])=[O:8].[Cu](C#N)[C:14]#[N:15]>>[C:14]([C:2]1[CH:3]=[N:4][CH:5]=[C:6]([CH:12]=1)[C:7]([NH:9][CH2:10][CH3:11])=[O:8])#[N:15]

참가 물질

반응물 2

HCID 220497285-Bromo-N-ethylpyridine-3-carboxamide

HCID 178418260HCID 178418260, 화합물

생성물 1

HCID 22049754HCID 22049754, 화합물수율 31.8%

실험 절차

By the reaction in the same manner as in Example 42-ii) using 5-bromo-N-ethylnicotinamide (580 mg) and copper cyanide (350 mg), the title compound (141 mg) was obtained as colorless powder crystals.

후처리

customBy the reaction in the same manner as in Example 42-ii)

출처 및 근거

ORD 기록: ord-efbc557ad97b47129fa512d6b680741a
출처 데이터셋: uspto-grants-2006_06
DOI: 10.6084/m9.figshare.5104873.v1
특허 번호: US07067537B2

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