HCID 22049741, 화합물 → HCID 135819832, 화합물

반응식

Br[CH2:2][C:3]([C:5]1[CH:6]=[N:7][CH:8]=[CH:9][C:10]=1[CH3:11])=O.C([O:16][C:17]1[N:22]=[CH:21][C:20]([C:23](=[S:25])[NH2:24])=[CH:19][CH:18]=1)(C)(C)C>>[CH3:11][C:10]1[CH:9]=[CH:8][N:7]=[CH:6][C:5]=1[C:3]1[N:24]=[C:23]([C:20]2[CH:19]=[CH:18][C:17](=[O:16])[NH:22][CH:21]=2)[S:25][CH:2]=1

참가 물질

반응물 2

HCID 22049741HCID 22049741, 화합물

HCID 220497832-Bromo-1-(4-methylpyridin-3-yl)ethan-1-one

생성물 1

HCID 135819832HCID 135819832, 화합물수율 56.1%

실험 절차

By the reaction in the same manner as in Example 25-iii) using 2-bromo-1-(4-methylpyridin-3-yl)ethanone hydrobromate (188 mg) and 6-tert-butoxy-3-pyridinecarbothioamide (167 mg), the title compound (120 mg) was obtained as colorless powder crystals.

후처리

customBy the reaction in the same manner as in Example 25-iii)

출처 및 근거

ORD 기록: ord-b0ff831c3f2e4d68be988700ce5b541e
출처 데이터셋: uspto-grants-2006_06
DOI: 10.6084/m9.figshare.5104873.v1
특허 번호: US07067537B2

반응 노트

불러오는 중…