Huagongshe화공사 화학 정보 인쇄 보고서 · 연구 참고용
Phosphate → Methyl-phenyl-carbamic Acid 4-(4-chloromethyl-thiazol-2-yl)-phenyl Ester
참여 물질
| 역할 | 이름 | HCID | 투입량 |
|---|---|---|---|
| 반응물 | Phosphate | HCID 1061 | — |
| 반응물 | Carbamic chloride, N-methyl-N-phenyl- | HCID 77969 | — |
| 반응물 | 4-[4-(Chloromethyl)-1,3-thiazol-2-yl]phenol | HCID 605504 | — |
| 생성물 | Methyl-phenyl-carbamic Acid 4-(4-chloromethyl-thiazol-2-yl)-phenyl Ester | HCID 10172371 | — |
반응 단계
The title compound was prepared from 4-(4-chloromethyl-thiazol-2-yl)-phenol and N-methyl-N-phenylcarbamoyl chloride. The aqueous phase was adjusted to PH 7.0 (phosphate buffer) before extraction with ethyl acetate. The crude product was subjected to preparative HPLC (21%, white crystals). HPLC-MS m/z=359.0 (M+1), Rt: 4.60.
출처 및 근거
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| 특허 번호 | US07067517B2 |
| 출처 데이터셋 | uspto-grants-2006_06 |
| ORD ID | ord-5baaf7edaa4b4e028643d510fc725e02 |
| 출처 메모 | uspto-grants-2006_06 |