Carbamic chloride, N-methyl-N-phenyl- → Methyl-phenyl-carbamic Acid 4-[(pyridine-2-carbonyl)-amino]-phenyl Ester

반응식

[OH:1][C:2]1[CH:7]=[CH:6][C:5]([NH:8][C:9]([C:11]2[CH:16]=[CH:15][CH:14]=[CH:13][N:12]=2)=[O:10])=[CH:4][CH:3]=1.[CH3:17][N:18]([C:22]1[CH:27]=[CH:26][CH:25]=[CH:24][CH:23]=1)[C:19](Cl)=[O:20]>>[N:12]1[CH:13]=[CH:14][CH:15]=[CH:16][C:11]=1[C:9]([NH:8][C:5]1[CH:4]=[CH:3][C:2]([O:1][C:19](=[O:20])[N:18]([CH3:17])[C:22]2[CH:27]=[CH:26][CH:25]=[CH:24][CH:23]=2)=[CH:7][CH:6]=1)=[O:10]

참가 물질

반응물 2

HCID 77969Carbamic chloride, N-methyl-N-phenyl-

HCID 11356337HCID 11356337, 화합물

생성물 1

HCID 10215434Methyl-phenyl-carbamic Acid 4-[(pyridine-2-carbonyl)-amino]-phenyl Ester

실험 절차

The title product was prepared from pyridine-2-carboxylic acid (4-hydroxy-phenyl)-amide and N-methyl-N-phenylcarbamoyl chloride. The crude product was subjected to preparative HPLC (41%,). HPLC-MS: m/z=348.1 (M+1); Rt: 4.00 min.

출처 및 근거

ORD 기록: ord-b6edb0acd33c462f8a63d7e467697515
출처 데이터셋: uspto-grants-2006_06
DOI: 10.6084/m9.figshare.5104873.v1
특허 번호: US07067517B2

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