Huagongshe화공사 화학 정보 인쇄 보고서 · 연구 참고용
Potassium Bromide → 4-(2-Chloro-6-fluoro-benzyl)-piperazine-1-carboxylic Acid 4-(5-trifluoromethyl-pyridin-2-yloxy)-phenyl Ester
참여 물질
| 역할 | 이름 | HCID | 투입량 |
|---|---|---|---|
| 반응물 | Potassium Bromide | HCID 253877 | — |
| 반응물 | 1-((2-Chloro-6-fluorophenyl)methyl)piperazine | HCID 735737 | — |
| 반응물 | 4-(5-Trifluoromethylpyridin-2-yloxy)-phenyl chloroformate | HCID 22047762 | — |
| 용매 | Ethanol | HCID 702 | — |
| 생성물 | 4-(2-Chloro-6-fluoro-benzyl)-piperazine-1-carboxylic Acid 4-(5-trifluoromethyl-pyridin-2-yloxy)-phenyl Ester | HCID 57455831 | — |
반응 단계
The hydrochloride of the title compound was prepared from 4-(5-trifluoromethyl-pyridin-2-yloxy)-phenyl chloroformate and 1-(2-chloro-6-fluorobenzyl)piperazine. White crystals, m.p. 204–205° C. (from ethanol); HPLC-MS m/z=510 (M+H); IR (KBr): ν 1726 (C═O) cm−1;
출처 및 근거
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| 특허 번호 | US07067517B2 |
| 출처 데이터셋 | uspto-grants-2006_06 |
| ORD ID | ord-7168c1c05d8e4081ba020e1c3875c208 |
| 출처 메모 | uspto-grants-2006_06 |