3-Chloro-1-propanol → N-{3-[1-(6-Hydroxyhexyl)-4-piperidinyl]phenyl}-2-methylpropanamide

HRID 1832441

반응식

HRID 1832441 반응식
OCCCN1CC[CH:8]([C:11]2[CH:12]=[C:13]([C:17](C)(C)[C:18](N)=[O:19])C=CC=2)CC1.ClCCCO.[CH3:28][CH:29]([CH3:45])[C:30]([NH:32][C:33]1[CH:38]=[CH:37][CH:36]=[C:35]([CH:39]2[CH2:44][CH2:43][NH:42][CH2:41][CH2:40]2)[CH:34]=1)=[O:31]>>[OH:19][CH2:18][CH2:17][CH2:13][CH2:12][CH2:11][CH2:8][N:42]1[CH2:43][CH2:44][CH:39]([C:35]2[CH:34]=[C:33]([NH:32][C:30](=[O:31])[CH:29]([CH3:45])[CH3:28])[CH:38]=[CH:37][CH:36]=2)[CH2:40][CH2:41]1

참가 물질

4

반응물 3

HCID 123133-Chloro-1-propanolHCID 167572552-methyl-N-[3-(4-piperidyl)phenyl]propanamideHCID 86760114{3-[1-(3-Hydroxypropyl)-4-piperidinyl]phenyl}-2-methylpropanamide

생성물 1

HCID 22049040N-{3-[1-(6-Hydroxyhexyl)-4-piperidinyl]phenyl}-2-methylpropanamide

실험 절차

N-({3-[1-(3-HYDROXYPROPYL)-4-PIPERIDINYL]PHENYL}-2-METHYLPROPANAMIDE: Prepared by Procedure G and Scheme B1 using 3-chloro-1-propanol and 2-methyl-N-[3-(4-piperidinyl)phenyl]propanamide: ESMS m/e: 305.3 (M+H)+.

출처 및 근거

ORD 기록
ord-363014aee296464aab276019f41856ad
출처 데이터셋
uspto-grants-2006_06
특허 번호
US07067534B1

연결된 노트

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