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Huagongshe화공사 화학 정보 인쇄 보고서 · 연구 참고용
HRID 1832452생성일: 2026년 10월 25일

3-(2,6-Dichlorophenyl)-5-methylisoxazole-4-carbonyl chloride → (1S)-3-{4-[3-(Isobutyrylamino)phenyl]-1-piperidinyl}-1-phenylpropyl 3-(2,6-dichlorophenyl)-5-methyl-4-isoxazolecarboxylate

https://huagongshe.com/reaction/1832452

반응식

참여 물질

역할이름HCID투입량
반응물3-(2,6-Dichlorophenyl)-5-methylisoxazole-4-carbonyl chlorideHCID 78212—
반응물N-(3-{1-[(3S)-3-Hydroxy-3-Phenylpropyl]-4-Piperidinyl}Phenyl)-2-MethylpropanamideHCID 60078700—
생성물(1S)-3-{4-[3-(Isobutyrylamino)phenyl]-1-piperidinyl}-1-phenylpropyl 3-(2,6-dichlorophenyl)-5-methyl-4-isoxazolecarboxylateHCID 58651314—

반응 단계

Prepared by Procedure Q1 and Scheme C2 (TEA) using N-(3-{1-[(3S)-3-hydroxy-3-phenylpropyl]-4-piperidinyl}phenyl)-2-methylpropanamide and 3-(2,6-dichlorophenyl)-5-methyl-4-isoxazolecarbonyl chloride: ESMS m/e: 633.6 (M+H)+.

출처 및 근거

DOI10.6084/m9.figshare.5104873.v1
특허 번호US07067534B1
출처 데이터셋uspto-grants-2006_06
ORD IDord-65918d082c8e4c0faf63b705301e5421
출처 메모uspto-grants-2006_06