2,4,5-Trifluorophenol → 1-{[(2R)-3-chloro-2-methylpropyl]oxy}-2,4,5-trifluorobenzene

반응식

[F:1][C:2]1[CH:7]=[C:6]([F:8])[C:5]([F:9])=[CH:4][C:3]=1[OH:10].Br[CH2:12][C@@H:13]([CH3:16])[CH2:14][Cl:15]>>[Cl:15][CH2:14][C@H:13]([CH3:16])[CH2:12][O:10][C:3]1[CH:4]=[C:5]([F:9])[C:6]([F:8])=[CH:7][C:2]=1[F:1]

참가 물질

반응물 2

HCID 1231532,4,5-Trifluorophenol

HCID 5479122(2S)-1-bromo-3-chloro-2-methylpropane

생성물 1

HCID 695238651-{[(2R)-3-chloro-2-methylpropyl]oxy}-2,4,5-trifluorobenzene

실험 절차

Prepared by Procedure U and Scheme AK using 2,4,5-trifluorophenol and (2S)-1-bromo-3-chloro-2-methylpropane.

후처리

customPrepared by Procedure U and Scheme AK

출처 및 근거

ORD 기록: ord-d768b9f357aa4624af5fe979f6d4fb8d
출처 데이터셋: uspto-grants-2006_06
DOI: 10.6084/m9.figshare.5104873.v1
특허 번호: US07067534B1

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