Hydrazine, 1-naphthalenyl-, hydrochloride (1:1) → 2-Methyl-N-(3-{1-[3-(2-phenyl-1H-benzo[G]indol-3-YL)propyl]-4-piperidinyl}phenyl)propanamide

HRID 1832586

반응식

HRID 1832586 반응식
[CH3:1][CH:2]([CH3:30])[C:3]([NH:5][C:6]1[CH:11]=[CH:10][CH:9]=[C:8]([CH:12]2[CH2:17][CH2:16][N:15]([CH2:18][CH2:19][CH2:20][CH2:21][C:22](=O)[C:23]3[CH:28]=[CH:27][CH:26]=[CH:25][CH:24]=3)[CH2:14][CH2:13]2)[CH:7]=1)=[O:4].Cl.[C:32]1([NH:42]N)[C:41]2[C:36](=[CH:37][CH:38]=[CH:39][CH:40]=2)[CH:35]=[CH:34][CH:33]=1>>[CH3:1][CH:2]([CH3:30])[C:3]([NH:5][C:6]1[CH:11]=[CH:10][CH:9]=[C:8]([CH:12]2[CH2:17][CH2:16][N:15]([CH2:18][CH2:19][CH2:20][C:21]3[C:33]4[C:32](=[C:41]5[CH:40]=[CH:39][CH:38]=[CH:37][C:36]5=[CH:35][CH:34]=4)[NH:42][C:22]=3[C:23]3[CH:28]=[CH:27][CH:26]=[CH:25][CH:24]=3)[CH2:14][CH2:13]2)[CH:7]=1)=[O:4]

참가 물질

3

반응물 2

HCID 519949Hydrazine, 1-naphthalenyl-, hydrochloride (1:1)HCID 220493932-methyl-N-(3-[1-(5-oxo-5-phenylpentyl)-4-piperidinyl]phenyl}propanamide

생성물 1

HCID 220490722-Methyl-N-(3-{1-[3-(2-phenyl-1H-benzo[G]indol-3-YL)propyl]-4-piperidinyl}phenyl)propanamide

실험 절차

Prepared by Procedure E and Scheme M using 2-methyl-N-{3-[1-(5-oxo-5-phenylpentyl)-4-piperidinyl]phenyl}propanamide and 1-(1-naphthyl)hydrazine hydrochloride: ESMS m/e: 530.2 (M+H)+.

후처리

  1. customPrepared by Procedure E and Scheme M

출처 및 근거

ORD 기록
ord-03f7770e42864833a046df7ba6aef5cf
출처 데이터셋
uspto-grants-2006_06
특허 번호
US07067534B1

연결된 노트

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