2-Methoxyphenylhydrazine Hydrochloride → N-(3-{1-[2-(7-Methoxy-2-phenyl-1H-indol-3-YL)ethyl]-4-piperidinyl}phenyl)-2-methylpropanamide

HRID 1832598노트

반응식

HRID 1832598 반응식
[CH3:1][CH:2]([CH3:29])[C:3]([NH:5][C:6]1[CH:11]=[CH:10][CH:9]=[C:8]([CH:12]2[CH2:17][CH2:16][N:15]([CH2:18][CH2:19][CH2:20][C:21](=O)[C:22]3[CH:27]=[CH:26][CH:25]=[CH:24][CH:23]=3)[CH2:14][CH2:13]2)[CH:7]=1)=[O:4].Cl.[CH3:31][O:32][C:33]1[CH:38]=[CH:37][CH:36]=[CH:35][C:34]=1[NH:39]N>>[CH3:31][O:32][C:33]1[CH:38]=[CH:37][CH:36]=[C:35]2[C:34]=1[NH:39][C:21]([C:22]1[CH:27]=[CH:26][CH:25]=[CH:24][CH:23]=1)=[C:20]2[CH2:19][CH2:18][N:15]1[CH2:16][CH2:17][CH:12]([C:8]2[CH:7]=[C:6]([NH:5][C:3](=[O:4])[CH:2]([CH3:29])[CH3:1])[CH:11]=[CH:10][CH:9]=2)[CH2:13][CH2:14]1

참가 물질

3

반응물 2

HCID 28494452-Methoxyphenylhydrazine HydrochlorideHCID 220490202-methyl-N-{3-[1-(4-oxo-4-phenylbutyl)-4-piperidinyl]phenyl}propanamide

생성물 1

HCID 22049202N-(3-{1-[2-(7-Methoxy-2-phenyl-1H-indol-3-YL)ethyl]-4-piperidinyl}phenyl)-2-methylpropanamide

실험 절차

Prepared by Procedure E and Scheme M using 2-methyl-N-{3-[1-(4-oxo-4-phenylbutyl)-4-piperidinyl]phenyl}propanamide and 1-(2-methoxyphenyl)hydrazine hydrochloride: ESMS m/e: 496.2 (M+H)+.

후처리

  1. customPrepared by Procedure E and Scheme M

출처 및 근거

ORD 기록
ord-38006b4fa5a84a4f9bbaca914827f7e7
출처 데이터셋
uspto-grants-2006_06
특허 번호
US07067534B1

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