P-Cresol → N-[3-(1-{[6-(2-Fluorophenyl)-1H-indol-3-YL]methyl}-4-piperidinyl)phenyl]-2-methylpropanamide

반응식

[F:1][C:2]1[CH:7]=[CH:6][CH:5]=[CH:4][C:3]=1[C:8]1[CH:16]=[C:15]2[C:11]([CH:12]=[CH:13][NH:14]2)=[CH:10][CH:9]=1.[CH3:17][CH:18]([CH3:34])[C:19]([NH:21][C:22]1[CH:27]=[CH:26][CH:25]=[C:24]([CH:28]2[CH2:33][CH2:32][NH:31][CH2:30][CH2:29]2)[CH:23]=1)=[O:20].[CH3:35]C1C=CC(OC2C=C3C(=CC=2)NC=C3)=CC=1.BrC1C=C2C(=CC=1)NC=C2.C1C(O)=CC=C(C)C=1>>[F:1][C:2]1[CH:7]=[CH:6][CH:5]=[CH:4][C:3]=1[C:8]1[CH:16]=[C:15]2[C:11]([C:12]([CH2:35][N:31]3[CH2:32][CH2:33][CH:28]([C:24]4[CH:23]=[C:22]([NH:21][C:19](=[O:20])[CH:18]([CH3:34])[CH3:17])[CH:27]=[CH:26][CH:25]=4)[CH2:29][CH2:30]3)=[CH:13][NH:14]2)=[CH:10][CH:9]=1