N-[3-(4-Piperidinyl)phenyl]propanamide → N-(3-{1-[5-(3-Fluorophenyl)-5-oxopentyl]-4-piperidinyl}phenyl)propanamide

HRID 1832704

반응식

HRID 1832704 반응식
Cl[CH2:2][CH2:3][CH2:4][CH2:5][C:6]([C:8]1[CH:13]=[CH:12][CH:11]=[C:10]([F:14])[CH:9]=1)=[O:7].[NH:15]1[CH2:20][CH2:19][CH:18]([C:21]2[CH:22]=[C:23]([NH:27][C:28](=[O:31])[CH2:29][CH3:30])[CH:24]=[CH:25][CH:26]=2)[CH2:17][CH2:16]1>>[F:14][C:10]1[CH:9]=[C:8]([C:6](=[O:7])[CH2:5][CH2:4][CH2:3][CH2:2][N:15]2[CH2:20][CH2:19][CH:18]([C:21]3[CH:22]=[C:23]([NH:27][C:28](=[O:31])[CH2:29][CH3:30])[CH:24]=[CH:25][CH:26]=3)[CH2:17][CH2:16]2)[CH:13]=[CH:12][CH:11]=1

참가 물질

3

반응물 2

HCID 22048836N-[3-(4-Piperidinyl)phenyl]propanamideHCID 220491125-Chloro-1-(3-fluorophenyl)-1-oxopentane

생성물 1

HCID 22049233N-(3-{1-[5-(3-Fluorophenyl)-5-oxopentyl]-4-piperidinyl}phenyl)propanamide

실험 절차

Prepared by Procedure K and Scheme B1 using 5-chloro-1-(3-fluorophenyl)-1-pentanone and N-[3-(4-piperidinyl)phenyl]propanamide: ESMS m/e: 411.2 (M+H)+.

후처리

  1. customPrepared by Procedure K and Scheme B1

출처 및 근거

ORD 기록
ord-496f04eff92e43d39d86d7c8bb03ae97
출처 데이터셋
uspto-grants-2006_06
특허 번호
US07067534B1

연결된 노트

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