3-Chloropropyl phenyl sulfide → N-(3-{1-[3-(Phenylsulfanyl)propyl]-4-piperidinyl}phenyl)cyclopropanecarboxamide

HRID 1832729노트

반응식

HRID 1832729 반응식
Cl[CH2:2][CH2:3][CH2:4][S:5][C:6]1[CH:11]=[CH:10][CH:9]=[CH:8][CH:7]=1.[NH:12]1[CH2:17][CH2:16][CH:15]([C:18]2[CH:19]=[C:20]([NH:24][C:25]([CH:27]3[CH2:29][CH2:28]3)=[O:26])[CH:21]=[CH:22][CH:23]=2)[CH2:14][CH2:13]1>>[C:6]1([S:5][CH2:4][CH2:3][CH2:2][N:12]2[CH2:17][CH2:16][CH:15]([C:18]3[CH:19]=[C:20]([NH:24][C:25]([CH:27]4[CH2:28][CH2:29]4)=[O:26])[CH:21]=[CH:22][CH:23]=3)[CH2:14][CH2:13]2)[CH:11]=[CH:10][CH:9]=[CH:8][CH:7]=1

참가 물질

3

반응물 2

HCID 2696063-Chloropropyl phenyl sulfideHCID 22048669N-[3-(4-Piperidinyl)phenyl]cyclopropanecarboxamide

생성물 1

HCID 22049150N-(3-{1-[3-(Phenylsulfanyl)propyl]-4-piperidinyl}phenyl)cyclopropanecarboxamide

실험 절차

Prepared by Procedure G and Scheme B1 using [(3-chloropropyl)sulfanyl]benzene and N-[3-(4-piperidinyl)phenyl]cyclopropanecarboxamide: ESMS m/e: 395.1 (M+H)+.

후처리

  1. customPrepared by Procedure G and Scheme B1

출처 및 근거

ORD 기록
ord-c9ff80ca184e4ae9b338d3512ad9b788
출처 데이터셋
uspto-grants-2006_06
특허 번호
US07067534B1

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