Huagongshe화공사 화학 정보 인쇄 보고서 · 연구 참고용
Chlorine monoxide → Ethyl 5-Hydroxy-4-Methyl-7-(3-Methyl-2-Octyl)-Coumarin-3-Propionate
참여 물질
| 역할 | 이름 | HCID | 투입량 |
|---|---|---|---|
| 반응물 | Chlorine monoxide | HCID 24646 | — |
| 반응물 | Diethyl 2-acetylglutarate | HCID 73915 | — |
| 반응물 | 5-(3-Methyloctan-2-yl)benzene-1,3-diol | HCID 258176 | — |
| 생성물 | Ethyl 5-Hydroxy-4-Methyl-7-(3-Methyl-2-Octyl)-Coumarin-3-Propionate | HCID 22765004 | — |
반응 단계
A mixture of 262 g. (1.109 mole) of 5-(3-methyl-2-octyl)resorcinol, 283 g. (1.23 mole) of diethyl α-acetylglutarate, and 170 g. (1.11 mole) of phorphorus oxychloride protected from atmospheric mositure is stirred at room temperature for 12 days. The mixture is taken up in benzene-ether and the solution is washed several times with water, aqueous sodium bicarbonate, water and dried over anhydrous magnesium sulfate. After removal of the solvent, 441 g. of an oil is obtained, which solidifies on standing.
출처 및 근거
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| 특허 번호 | US04066667 |
| 출처 데이터셋 | uspto-grants-1978_01 |
| ORD ID | ord-512ec0595d0e4f4f9427f04f33fd8ab3 |
| 출처 메모 | uspto-grants-1978_01 |