2-Diethylamino-4-imino-2-thiazoline hydrochloride → HCID 178463884, 화합물

반응식

[I:1][C:2]1[C:3]([O:16][CH3:17])=[C:4]2[C:8](=[C:9]([O:12][CH3:13])[C:10]=1[I:11])[C:7](=[NH:14])[NH:6][C:5]2=N.[ClH:18].[CH2:19]([N:21]([CH2:28][CH3:29])[C:22]1[S:23][CH2:24][C:25](=[NH:27])[N:26]=1)[CH3:20].Cl.N1(C2SCC(=N)N=2)CCCCC1>>[ClH:18].[NH2:14][CH:7]1[C:8]2[C:4](=[C:3]([O:16][CH3:17])[C:2]([I:1])=[C:10]([I:11])[C:9]=2[O:12][CH3:13])[C:5](=[C:24]2[S:23][C:22]([N:21]([CH2:28][CH3:29])[CH2:19][CH3:20])=[N:26][C:25]2=[NH:27])[NH:6]1

참가 물질

반응물 3

HCID 162452432-Diethylamino-4-imino-2-thiazoline hydrochloride

HCID 162452962-Piperidino-4-imino-2-thiazoline hydrochloride

HCID 178493652HCID 178493652, 화합물

생성물 1

HCID 178463884HCID 178463884, 화합물

실험 절차

Following the procedure described in Example 9, part B above but using equivalent amounts of 5,6-diiodo-4,7-dimethoxy-1,3-diiminoisoindoline and 2-diethylamino-4-imino-2-thiazoline hydrochloride in place of 1,3-diiminoisoindoline and 2-piperidino-4-imino-2-thiazoline hydrochloride respectively, there is obtained as the product 1-amino-5,6-diiodo-4,7-dimethoxy-3-(2-diethylamino-4-imino-2-thiazolin-5-ylidene)isoindoline hydrochloride.