HCID 21388802, 화합물 → 5-Cyano-2-(4-n-propoxyphenyl)-pyrimidine
반응식
Cl[C:2]1[C:7]([C:8]#[N:9])=[CH:6][N:5]=[C:4]([C:10]2[CH:15]=[CH:14][C:13]([O:16][CH2:17][CH2:18][CH3:19])=[CH:12][CH:11]=2)[N:3]=1>[Zn].O1CCOCC1>[C:8]([C:7]1[CH:6]=[N:5][C:4]([C:10]2[CH:15]=[CH:14][C:13]([O:16][CH2:17][CH2:18][CH3:19])=[CH:12][CH:11]=2)=[N:3][CH:2]=1)#[N:9]참가 물질
4
실험 절차
4.7 G. of 4-chloro-5-cyano-2-(4-n-propoxyphenyl)-pyrimidine are reacted in 230 ml. of 50% dioxane with 20.0 g. of pre-treated zinc dust and worked up after the reaction in a manner analogous to that described in Example 13. There is obtained 5-cyano-2-(4-n-propoxyphenyl)-pyrimidine as colorless crystals having a melting point of 146.2°-146.6° C, which on cooling are nematic (monotropic) at 137.0° C.
후처리
- customafter the reaction in a manner analogous to
출처 및 근거
- ORD 기록
- ord-662cb6e7e8784f0b923b8bf9be12cca8
- 출처 데이터셋
- uspto-grants-1978_01
- 특허 번호
- US04066570
반응 노트
불러오는 중…