Ethanol → 3-Ethoxy-7-chloro-benzo-1,2,4-triazine

HRID 1834023노트

반응식

HRID 1834023 반응식
Cl[C:2]1[N:3]=[N:4][C:5]2[CH:11]=[C:10]([Cl:12])[CH:9]=[CH:8][C:6]=2[N:7]=1.[C-]#N.[Na+].[CH2:16]([OH:18])[CH3:17]>>[CH2:16]([O:18][C:2]1[N:3]=[N:4][C:5]2[CH:11]=[C:10]([Cl:12])[CH:9]=[CH:8][C:6]=2[N:7]=1)[CH3:17]

참가 물질

4

반응물 3

HCID 702EthanolHCID 8929Sodium CyanideHCID 205554783,7-Dichloro-1,2,4-benzotriazine

생성물 1

HCID 213882453-Ethoxy-7-chloro-benzo-1,2,4-triazine

실험 절차

A suspension of 20.2 g (0.1 mole) of 3,7-dichlorobenzo-1,2,4-triazine and 12.2 g (0.25 mole) of sodium cyanide in 200 ml of ethanol was boiled under reflux for 2 hours. The salts were filtered off and the filtrate was evaporated in vacuo. The residue was stirred with water and cooled in ice for some time. The crystallized mass was filtered off and recrystallized from wash benzine. 17.6 g, that is to say 84% of theory, of 3-ethoxy-7-chloro-benzo-1,2,4-triazine with a melting point of 90°-92° C were obtained.

후처리

  1. temperatureunder reflux for 2 hours
  2. filtrationThe salts were filtered off
  3. customthe filtrate was evaporated in vacuo
  4. temperaturecooled in ice for some time
  5. filtrationThe crystallized mass was filtered off
  6. customrecrystallized
  7. washfrom wash benzine

출처 및 근거

ORD 기록
ord-34c55ef53e50409ea70f87a65c8960be
출처 데이터셋
uspto-grants-1978_01
특허 번호
US04067981

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