N-(2-{[(4-Bromo-1,2-thiazol-3-yl)methyl]sulfanyl}ethyl)-N'-methylthiourea → N-cyano-N'-[2-((4-bromo-3-isothiazolyl)methylthio)ethyl]-N"-methylguanidine

HRID 1834621

반응식

HRID 1834621 반응식
[CH3:1][NH:2][C:3]([NH:5][CH2:6][CH2:7][S:8][CH2:9][C:10]1[C:14]([Br:15])=[CH:13][S:12][N:11]=1)=S.[N:16]#[C:17][NH2:18].[Pb]>>[C:17]([NH:18][C:3]([NH:5][CH2:6][CH2:7][S:8][CH2:9][C:10]1[C:14]([Br:15])=[CH:13][S:12][N:11]=1)=[N:2][CH3:1])#[N:16]

참가 물질

3

반응물 2

HCID 12923381N-(2-{[(4-Bromo-1,2-thiazol-3-yl)methyl]sulfanyl}ethyl)-N'-methylthioureaHCID 22262466CH2N2Pb

생성물 1

HCID 54571990N-cyano-N'-[2-((4-bromo-3-isothiazolyl)methylthio)ethyl]-N"-methylguanidine

실험 절차

Reaction of N-methyl-N'-[2-((4-bromo-3-isothiazolyl)methylthio)ethyl]thiourea with lead cyanamide by the procedure of Example 121 gives N-cyano-N'-[2-((4-bromo-3-isothiazolyl)methylthio)ethyl]-N"-methylguanidine.

출처 및 근거

ORD 기록
ord-8407932c08854c90bbdd733897c28d27
출처 데이터셋
uspto-grants-1978_01
특허 번호
US04070475

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