HCID 22797455, 화합물 → HCID 22797482, 화합물
반응식
[OH:1][CH2:2][C@@:3]12[C@@H:20]3[C@H:11]([C@H:12]4[C@@:16]([CH2:18][CH2:19]3)([CH3:17])[C@@H:15]([O:21][Si:22]([C:35]3[CH:40]=[CH:39][CH:38]=[CH:37][CH:36]=3)([C:29]3[CH:34]=[CH:33][CH:32]=[CH:31][CH:30]=3)[C:23]3[CH:28]=[CH:27][CH:26]=[CH:25][CH:24]=3)[CH2:14][CH2:13]4)[CH2:10][CH2:9][C:8]1=[C:7]([CH3:41])[C:6](=[O:42])[CH2:5][CH2:4]2.CC(C)=O.OS(O)(=O)=O.O=[Cr](=O)=O>CC(C)=O>[CH3:41][C:7]1[C:6](=[O:42])[CH2:5][CH2:4][C@@:3]2([CH:2]=[O:1])[C:8]=1[CH2:9][CH2:10][C@@H:11]1[C@@H:20]2[CH2:19][CH2:18][C@@:16]2([CH3:17])[C@H:12]1[CH2:13][CH2:14][C@@H:15]2[O:21][Si:22]([C:23]1[CH:24]=[CH:25][CH:26]=[CH:27][CH:28]=1)([C:35]1[CH:40]=[CH:39][CH:38]=[CH:37][CH:36]=1)[C:29]1[CH:30]=[CH:31][CH:32]=[CH:33][CH:34]=1참가 물질
4
실험 절차
To a solution of 19-hydroxy-4-methyl-17β-triphenylsiloxy-androst-4-en-3-one in acetone chilled to 10° C. is added one equivalent of Jones Reagent. After 30 miutes, the acetone layer is decanted and poured onto water with vigorous stirring. The solid is filtered, dried in a vacuum oven and crystallized from hexane to yield 4-methyl-17β-triphenylsiloxy-4-androstene-3,19-dione.