Methyl Chloride → N-oleoylaminopropyl-N,N,N-trimethylammonium chloride

반응식

[C:1]([NH:20][CH2:21][CH2:22][CH2:23][N:24]([CH3:26])[CH3:25])(=[O:19])[CH2:2][CH2:3][CH2:4][CH2:5][CH2:6][CH2:7][CH2:8]/[CH:9]=[CH:10]\[CH2:11][CH2:12][CH2:13][CH2:14][CH2:15][CH2:16][CH2:17][CH3:18].[CH3:27][Cl:28]>>[Cl-:28].[C:1]([NH:20][CH2:21][CH2:22][CH2:23][N+:24]([CH3:27])([CH3:26])[CH3:25])(=[O:19])[CH2:2][CH2:3][CH2:4][CH2:5][CH2:6][CH2:7][CH2:8]/[CH:9]=[CH:10]\[CH2:11][CH2:12][CH2:13][CH2:14][CH2:15][CH2:16][CH2:17][CH3:18]

참가 물질

반응물 2

HCID 6327Methyl Chloride

HCID 6436063N-(3-(Dimethylamino)propyl)oleamide

생성물 1

HCID 86586933N-oleoylaminopropyl-N,N,N-trimethylammonium chloride

실험 절차

A synthetic operation was carried out using oleoylaminopropyl-N,N-dimethylamine synthesized in the above Synthetic Example 15 and methyl chloride in the same manner as in Synthetic Example 13 to obtain the target N-oleoylaminopropyl-N,N,N-trimethylammonium chloride (a″-6).

출처 및 근거

ORD 기록: ord-8e365b707c8042338b84ad0a55199566
출처 데이터셋: uspto-grants-2004_08
DOI: 10.6084/m9.figshare.5104873.v1
특허 번호: US06770617B2

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