HCID 12988784, 화합물 → 1,2-Benzenediamine, 4-[2-(4-morpholinyl)ethoxy]-

HRID 1835936노트

반응식

HRID 1835936 반응식
[N:1]1([CH2:7][CH2:8][O:9][C:10]2[CH:15]=[CH:14][C:13]([NH2:16])=[C:12]([N+:17]([O-])=O)[CH:11]=2)[CH2:6][CH2:5][O:4][CH2:3][CH2:2]1>CCO.[Pd]>[N:1]1([CH2:7][CH2:8][O:9][C:10]2[CH:11]=[C:12]([NH2:17])[C:13]([NH2:16])=[CH:14][CH:15]=2)[CH2:6][CH2:5][O:4][CH2:3][CH2:2]1

참가 물질

4

반응물 1

HCID 12988784HCID 12988784, 화합물

생성물 1

HCID 129887851,2-Benzenediamine, 4-[2-(4-morpholinyl)ethoxy]-

시약·촉매·용매 2

HCID 23938Palladium촉매HCID 702Ethanol용매

실험 절차

To a solution 4-(2-morpholin-4-ylethoxy)-2-nitrophenylamine (1.0 eq) in EtOH was added Pd/C (0.1 eq). The reaction vessel was repeatedly purged with nitrogen, then stirred under a hydrogen atmosphere (1 atm) for 18 hours. The product was filtered through a Celite plug, and the plug washed with EtOH. The diamine was used without purification. LC/MS m/z 238.3 (MH+), Rt 0.295 minutes.

후처리

  1. customThe reaction vessel was repeatedly purged with nitrogen
  2. filtrationThe product was filtered through a Celite plug
  3. washthe plug washed with EtOH
  4. customThe diamine was used without purification

출처 및 근거

ORD 기록
ord-65b19035f1d54206b9785a1aae562ae2
출처 데이터셋
uspto-grants-2004_08
특허 번호
US06774237B2

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