2-(Bromomethyl)tetrahydro-2H-pyran → 7-Nitro-2-(tetrahydropyran-2-yl)methyl-2h-phthalazin-1-one

HRID 1836843

반응식

HRID 1836843 반응식
[N+:1]([C:4]1[CH:13]=[C:12]2[C:7]([CH:8]=[N:9][NH:10][C:11]2=[O:14])=[CH:6][CH:5]=1)([O-:3])=[O:2].[CH2:15]1[CH2:20][CH:19]([CH2:21]Br)[O:18][CH2:17][CH2:16]1>>[N+:1]([C:4]1[CH:13]=[C:12]2[C:7]([CH:8]=[N:9][N:10]([CH2:21][CH:19]3[CH2:20][CH2:15][CH2:16][CH2:17][O:18]3)[C:11]2=[O:14])=[CH:6][CH:5]=1)([O-:3])=[O:2]

참가 물질

3

실험 절차

Step (b) of Example 125 was repeated, except that the compound prepared in step (b) of Example 137 and tetrahydro-2H-pyran-2-methyl bromide were used as the starting compounds. Thus, 7-nitro-2-(tetrahydropyran-2-yl)methyl-2H-phthalazin-1-one was obtained.

출처 및 근거

ORD 기록
ord-b83091a9fb414ce099dd3e8fe3b6daa6
출처 데이터셋
uspto-grants-2004_08
특허 번호
US06777414B1

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