Methyl 3-(bromomethyl)benzoate → Methyl 3-[(2-amino-5-chloro-3-pyridinyl)oxy]methylbenzoate

HRID 1838082노트

반응식

HRID 1838082 반응식
[NH2:1][C:2]1[C:7]([OH:8])=[CH:6][C:5]([Cl:9])=[CH:4][N:3]=1.Br[CH2:11][C:12]1[CH:13]=[C:14]([CH:19]=[CH:20][CH:21]=1)[C:15]([O:17][CH3:18])=[O:16]>>[NH2:1][C:2]1[C:7]([O:8][CH2:11][C:12]2[CH:13]=[C:14]([CH:19]=[CH:20][CH:21]=2)[C:15]([O:17][CH3:18])=[O:16])=[CH:6][C:5]([Cl:9])=[CH:4][N:3]=1

참가 물질

3

반응물 2

HCID 517981Methyl 3-(bromomethyl)benzoateHCID 103132002-Amino-5-chloropyridin-3-ol

생성물 1

HCID 18752887Methyl 3-[(2-amino-5-chloro-3-pyridinyl)oxy]methylbenzoate

실험 절차

The title compound was prepared using the method of Preparation 22 from 2-amino-5-chloro-3-pyridinol and methyl 3-(bromomethyl)benzoate to give a tan solid:

후처리

  1. customto give a tan solid

출처 및 근거

ORD 기록
ord-e4bf22fae57c48d8b614f9cd4e3db170
출처 데이터셋
uspto-grants-2004_01
특허 번호
US06673789B2

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