5,6-bis(4-methoxyphenyl)-4-cyano-2H-pyridazin-3-one → 5,6-bis(4-Methoxyphenyl)-4-cyano-2-cyclopentylmethyl-2H-pyridazin-3-one

HRID 1840268노트

반응식

HRID 1840268 반응식
[CH3:1][O:2][C:3]1[CH:8]=[CH:7][C:6]([C:9]2[C:14]([C:15]3[CH:20]=[CH:19][C:18]([O:21][CH3:22])=[CH:17][CH:16]=3)=[N:13][NH:12][C:11](=[O:23])[C:10]=2[C:24]#[N:25])=[CH:5][CH:4]=1.[CH:26]1([CH2:31]Cl)[CH2:30][CH2:29][CH2:28][CH2:27]1>>[CH3:1][O:2][C:3]1[CH:8]=[CH:7][C:6]([C:9]2[C:14]([C:15]3[CH:20]=[CH:19][C:18]([O:21][CH3:22])=[CH:17][CH:16]=3)=[N:13][N:12]([CH2:31][CH:26]3[CH2:30][CH2:29][CH2:28][CH2:27]3)[C:11](=[O:23])[C:10]=2[C:24]#[N:25])=[CH:5][CH:4]=1

참가 물질

3

반응물 2

HCID 126885835,6-bis(4-methoxyphenyl)-4-cyano-2H-pyridazin-3-oneHCID 12815409(Chloromethyl)cyclopentane

생성물 1

HCID 155185105,6-bis(4-Methoxyphenyl)-4-cyano-2-cyclopentylmethyl-2H-pyridazin-3-one수율 42.4%

실험 절차

Using 5,6-bis(4-methoxyphenyl)-4-cyano-2H-pyridazin-3-one and cyclopentylmethyl chloride as starting materials, the procedures of Example 1 were repeated likewise, whereby the title compound was obtained in a yield of 42.4%.

출처 및 근거

ORD 기록
ord-3182c615678243178633329a28254011
출처 데이터셋
uspto-grants-2004_01
특허 번호
US06680316B1

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