alpha-Phenylcinnamic acid, (E)- → (R)-N-(1-Azabicyclo[2.2.2]oct-3-yl)(E-2,3-diphenylpropenamide)
반응식
Cl.Cl.[N:3]12[CH2:10][CH2:9][CH:6]([CH2:7][CH2:8]1)[C@@H:5]([NH2:11])[CH2:4]2.[C:12]1(/[C:18](=[CH:22]\[C:23]2[CH:28]=[CH:27][CH:26]=[CH:25][CH:24]=2)/[C:19](O)=[O:20])[CH:17]=[CH:16][CH:15]=[CH:14][CH:13]=1>>[N:3]12[CH2:10][CH2:9][CH:6]([CH2:7][CH2:8]1)[C@@H:5]([NH:11][C:19](=[O:20])/[C:18](/[C:12]1[CH:17]=[CH:16][CH:15]=[CH:14][CH:13]=1)=[CH:22]/[C:23]1[CH:28]=[CH:27][CH:26]=[CH:25][CH:24]=1)[CH2:4]2참가 물질
3
실험 절차
Prepared as free base by a method analogous to that described in Example 1 from (R)-1-azabicyclo[2.2.2]oct-3-ylamine dihydrochloride and E-2,3-diphenylpropenoic acid; MS (ES+) 333 (MH+).
후처리
- customPrepared as free base by a method analogous to
출처 및 근거
- ORD 기록
- ord-288a78f2b4f94bf29873c7241cdab3ec
- 출처 데이터셋
- uspto-grants-2004_01
- DOI