Huagongshe화공사 화학 정보 인쇄 보고서 · 연구 참고용
Quinuclidine, 3-amino-, dihydrochloride → (Rs)-n-(1-azabicyclo[2.2.2]oct-3-yl)[e-3-(2-trifluoromethylphenyl)propenamide]
참여 물질
| 역할 | 이름 | HCID | 투입량 |
|---|---|---|---|
| 반응물 | Quinuclidine, 3-amino-, dihydrochloride | HCID 197853 | — |
| 반응물 | 2-(Trifluoromethyl)cinnamic acid, (E)- | HCID 719625 | — |
| 생성물 | (Rs)-n-(1-azabicyclo[2.2.2]oct-3-yl)[e-3-(2-trifluoromethylphenyl)propenamide] | HCID 9945116 | — |
반응 단계
Prepared as a free base by a method analogous to that described in Example 1 from racemic 1-azabicyclo[2.2.2]oct-3-ylamine dihydrochloride and E-3-(2-trifluoromethylphenyl)propenoic acid; MS (ES+) 325 (MH+).
출처 및 근거
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| 특허 번호 | US06683090B1 |
| 출처 데이터셋 | uspto-grants-2004_01 |
| ORD ID | ord-20d1366df0bf4007a0db4970cb2f3893 |
| 출처 메모 | uspto-grants-2004_01 |