Huagongshe화공사 화학 정보 인쇄 보고서 · 연구 참고용
2-Furanacrylic acid → (S)-N-(1-Azabicyclo[2.2.2]oct-3-yl)[E-3-(2-furyl)propenamide]
참여 물질
| 역할 | 이름 | HCID | 투입량 |
|---|---|---|---|
| 반응물 | 2-Furanacrylic acid | HCID 643402 | — |
| 반응물 | (3S)-1-azabicyclo[2.2.2]octan-3-amine dihydrochloride | HCID 12494973 | — |
| 생성물 | (S)-N-(1-Azabicyclo[2.2.2]oct-3-yl)[E-3-(2-furyl)propenamide] | HCID 20613779 | — |
반응 단계
Prepared as a free base by a method analogous to that described in Example 1 from (S)-1-azabicyclo[2.2.2]oct-3-ylamine dihydrochloride and E-3-(2-furyl)propenoic acid; the compound was purified by chromatography on silica gel using ammoniated methanol/chloroform mixtures as the eluent, followed by recrystallization from ethyl acetate/hexane; MS (ES+) 247 (MH+).
출처 및 근거
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| 특허 번호 | US06683090B1 |
| 출처 데이터셋 | uspto-grants-2004_01 |
| ORD ID | ord-5eeea2a48aad4348bbcbd8f09047b1b8 |
| 출처 메모 | uspto-grants-2004_01 |