2-(4-Chloro-3-methylphenyl)-4,4,5,5-tetramethyl-1,3,2-dioxaborolane → 3-(4-Chloro-3-methyl-phenyl)-5-(2-methyl-imidazol-1-yl-methyl)-pyridine Hydrochloride

HRID 1841203노트

반응식

HRID 1841203 반응식
Br[C:2]1[CH:3]=[N:4][CH:5]=[C:6]([CH2:8][N:9]2[CH:13]=[CH:12][N:11]=[C:10]2[CH3:14])[CH:7]=1.[Cl:15][C:16]1[CH:21]=[CH:20][C:19](B2OC(C)(C)C(C)(C)O2)=[CH:18][C:17]=1[CH3:31]>>[ClH:15].[Cl:15][C:16]1[CH:21]=[CH:20][C:19]([C:2]2[CH:3]=[N:4][CH:5]=[C:6]([CH2:8][N:9]3[CH:13]=[CH:12][N:11]=[C:10]3[CH3:14])[CH:7]=2)=[CH:18][C:17]=1[CH3:31]

참가 물질

3

반응물 2

HCID 37676412-(4-Chloro-3-methylphenyl)-4,4,5,5-tetramethyl-1,3,2-dioxaborolaneHCID 234449653-Bromo-5-(2-methyl-imidazol-1-ylmethyl)-pyridine

생성물 1

HCID 234450523-(4-Chloro-3-methyl-phenyl)-5-(2-methyl-imidazol-1-yl-methyl)-pyridine Hydrochloride

실험 절차

The title compound, MS: m/e=298.3 (M+H+) was obtained as a white solid (73% yield) by the reaction of 3-bromo-5-(2-methyl-imidazol-1-yl-methyl)-pyridine with 2-(4-chloro-3-methyl-phenyl)-4,4,5,5-tetramethyl[1,3,2]-dioxaborolane.

출처 및 근거

ORD 기록
ord-5677ef9aa91d4002955b4fafde724450
출처 데이터셋
uspto-grants-2004_01
특허 번호
US06683097B2

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