HCID 23444959, 화합물 → Benzenamine, 3-(1,1-difluoroethyl)-4-fluoro-
반응식
[F:1][C:2]([C:5]1[CH:10]=[C:9]([N+:11]([O-])=O)[CH:8]=[CH:7][C:6]=1[F:14])([F:4])[CH3:3]>CO>[F:4][C:2]([C:5]1[CH:10]=[C:9]([NH2:11])[CH:8]=[CH:7][C:6]=1[F:14])([F:1])[CH3:3]참가 물질
3
실험 절차
To a solution of 2-(1,1-difluoro-ethyl)-1-fluoro-4-nitro-benzene (10.4 g, 50.6 mmol) in methanol (200 ml) palladium on carbon (10%, 4 g) was added and the resulting mixture was hydrogenated for 2 h at 20° C. After filtration of the catalyst the solvent was evaporated to yield the title compound as a yellow semi solid mass. (8.5 g, 96%). MS: m/e=175 (M+).
후처리
- filtrationAfter filtration of the catalyst the solvent
- customwas evaporated
출처 및 근거
- ORD 기록
- ord-be6e90cc8a1d4b64b97a43b17d197702
- 출처 데이터셋
- uspto-grants-2004_01
- 특허 번호
- US06683097B2
반응 노트
불러오는 중…