1-(2-Isopropylphenyl)piperazine → 1-[(5,6-Dimethyl-2-methoxypyrazin-3-yl)aminocarbonyl]-4-(2-isopropylphenyl)piperazine

HRID 1841451

반응식

HRID 1841451 반응식
[CH3:1][C:2]1[N:3]=[C:4]([NH:11][C:12](=[O:20])OC2C=CC=CC=2)[C:5]([O:9][CH3:10])=[N:6][C:7]=1[CH3:8].[CH:21]([C:24]1[CH:29]=[CH:28][CH:27]=[CH:26][C:25]=1[N:30]1[CH2:35][CH2:34][NH:33][CH2:32][CH2:31]1)([CH3:23])[CH3:22]>>[CH3:1][C:2]1[N:3]=[C:4]([NH:11][C:12]([N:33]2[CH2:34][CH2:35][N:30]([C:25]3[CH:26]=[CH:27][CH:28]=[CH:29][C:24]=3[CH:21]([CH3:23])[CH3:22])[CH2:31][CH2:32]2)=[O:20])[C:5]([O:9][CH3:10])=[N:6][C:7]=1[CH3:8]

참가 물질

3

반응물 2

HCID 36088221-(2-Isopropylphenyl)piperazineHCID 11173351Phenyl N-(5,6-dimethyl-2-methoxypyrazin-3-yl)carbamate

생성물 1

HCID 234463641-[(5,6-Dimethyl-2-methoxypyrazin-3-yl)aminocarbonyl]-4-(2-isopropylphenyl)piperazine수율 73%

실험 절차

Phenyl N-(5,6-dimethyl-2-methoxypyrazin-3-yl)carbamate and 1-(2-isopropylphenyl)piperazine were reacted by the same way with the example 1 to obtain the titled compound.

출처 및 근거

ORD 기록
ord-51ffab64370249b2911a71260de21dec
출처 데이터셋
uspto-grants-2004_01
특허 번호
US06683184B2

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