1-(2-Isopropylphenyl)piperazine → 1-[(2-Methoxyquinoxalin-3-yl)aminocarbonyl]-4-(2-isoprop-ylphenyl) piperazine

HRID 1841473

반응식

HRID 1841473 반응식
[CH3:1][O:2][C:3]1[C:12]([NH:13][C:14](=[O:22])OC2C=CC=CC=2)=[N:11][C:10]2[C:5](=[CH:6][CH:7]=[CH:8][CH:9]=2)[N:4]=1.[CH:23]([C:26]1[CH:31]=[CH:30][CH:29]=[CH:28][C:27]=1[N:32]1[CH2:37][CH2:36][NH:35][CH2:34][CH2:33]1)([CH3:25])[CH3:24]>>[CH3:1][O:2][C:3]1[C:12]([NH:13][C:14]([N:35]2[CH2:36][CH2:37][N:32]([C:27]3[CH:28]=[CH:29][CH:30]=[CH:31][C:26]=3[CH:23]([CH3:25])[CH3:24])[CH2:33][CH2:34]2)=[O:22])=[N:11][C:10]2[C:5](=[CH:6][CH:7]=[CH:8][CH:9]=2)[N:4]=1

참가 물질

3

반응물 2

HCID 36088221-(2-Isopropylphenyl)piperazineHCID 23446261Phenyl N-(2-methoxyquinoxalin-3-yl)carbamate

생성물 1

HCID 234462861-[(2-Methoxyquinoxalin-3-yl)aminocarbonyl]-4-(2-isoprop-ylphenyl) piperazine수율 77.5%

실험 절차

Phenyl N-(2-methoxyquinoxalin-3-yl)carbamate and 1-(2-isopropylphenyl)piperazine were reacted by the same way with the example 36 to obtain the titled compound.

출처 및 근거

ORD 기록
ord-41d9bd1597e24684a394828e307b43f1
출처 데이터셋
uspto-grants-2004_01
특허 번호
US06683184B2

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