4-Chlorophenyl chloroformate → (4-Hydroxy-phenyl)-methyl-carbamic acid 4-chloro-phenyl ester

반응식

S([O:5][C:6]1[CH:11]=[CH:10][C:9]([NH:12][CH3:13])=[CH:8][CH:7]=1)(O)(=O)=O.[CH:14]1[C:19]([O:20][C:21](Cl)=[O:22])=[CH:18][CH:17]=[C:16]([Cl:24])[CH:15]=1>>[Cl:24][C:16]1[CH:17]=[CH:18][C:19]([O:20][C:21](=[O:22])[N:12]([C:9]2[CH:10]=[CH:11][C:6]([OH:5])=[CH:7][CH:8]=2)[CH3:13])=[CH:14][CH:15]=1

참가 물질

반응물 2

HCID 1390594-Chlorophenyl chloroformate

HCID 10198132p-(N-methylamino)phenol sulfate

생성물 1

HCID 68614626(4-Hydroxy-phenyl)-methyl-carbamic acid 4-chloro-phenyl ester

실험 절차

In analogy to example 15.1, reaction of 4-methylaminophenol hemisulfate with 4-chlorophenylchloroformate yielded (4-Hydroxy-phenyl)-methyl-carbamic acid 4-chloro-phenyl ester, mp: 143-145° C., dec.; MS: 278 (MH+, 1Cl).

출처 및 근거

ORD 기록: ord-db1c3b80328e40de971e58b82c93fac1
출처 데이터셋: uspto-grants-2004_01
DOI: 10.6084/m9.figshare.5104873.v1
특허 번호: US06683201B2

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