4-(2,3-Difluoro-phenyl)-1,3-dihydro-indol-2-one → 5-(2-diethylamino-ethyl)-2-[4-(2,3-difluoro-phenyl)-2-oxo-1,2-dihydro-indol-3-ylidenemethyl]-3-methyl-5,6,7,8-tetrahydro-1H-pyrrolo[3,2-c]azepin-4-one

반응식

[CH2:1]([CH3:2])[N:3]([CH2:4][CH2:5][N:6]1[C:7](=[O:19])[c:8]2[c:9]([nH:13][c:14]([CH:17]=[O:18])[c:15]2[CH3:16])[CH2:10][CH2:11][CH2:12]1)[CH2:20][CH3:21].[F:22][c:23]1[c:24](-[c:30]2[c:31]3[c:35]([cH:36][cH:37][cH:38]2)[NH:34][C:33](=[O:39])[CH2:32]3)[cH:25][cH:26][cH:27][c:28]1[F:29]>>[CH2:1]([CH3:2])[N:3]([CH2:4][CH2:5][N:6]1[C:7](=[O:19])[c:8]2[c:9]([nH:13][c:14]([CH:17]=[C:32]3[c:31]4[c:30](-[c:24]5[c:23]([F:22])[c:28]([F:29])[cH:27][cH:26][cH:25]5)[cH:38][cH:37][cH:36][c:35]4[NH:34][C:33]3=[O:39])[c:15]2[CH3:16])[CH2:10][CH2:11][CH2:12]1)[CH2:20][CH3:21]