Huagongshe화공사 화학 정보 인쇄 보고서 · 연구 참고용
Aluminium lithium hydride → 2-(1-Benzothiophen-2-yl)ethan-1-amine
참여 물질
| 역할 | 이름 | HCID | 투입량 |
|---|---|---|---|
| 반응물 | Aluminium lithium hydride | HCID 21226445 | — |
| 반응물 | 2-(2-Nitroethenyl)-1-benzothiophene | HCID 66801639 | — |
| 용매 | Tetrahydrofuran | HCID 8028 | — |
| 생성물 | 2-(1-Benzothiophen-2-yl)ethan-1-amine | HCID 12666893 | 90.3% |
반응 단계
Using analogous reaction conditions and workup as described in Example 1, step 2, 2-(2-nitro-vinyl)-benzo[b]thiophene (I-9a: 2.1 g, 0.010 mol) in dry THF (30 mL) was reacted with LAH (0.81 g, 0.021 mol) in dry THF (20 mL) to afford 1.6 g of the product (87.91% yield).
출처 및 근거
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| 특허 번호 | US08946260B2 |
| 출처 데이터셋 | uspto-grants-2015_02 |
| ORD ID | ord-c0f4c3ad00464348aa8058b3b9ba2953 |
| 출처 메모 | uspto-grants-2015_02 |