Huagongshe화공사 화학 정보 인쇄 보고서 · 연구 참고용
3-(3-Fluorophenyl)-2-propenoic acid → 3-(3-Fluorophenyl)propionic acid
참여 물질
| 역할 | 이름 | HCID | 투입량 |
|---|---|---|---|
| 반응물 | 3-(3-Fluorophenyl)-2-propenoic acid | HCID 88606 | — |
| 촉매 | Palladium | HCID 23938 | — |
| 용매 | Methanol | HCID 887 | — |
| 생성물 | 3-(3-Fluorophenyl)propionic acid | HCID 2737489 | 80.69% |
반응 단계
3-(3-Fluorophenyl)acrylic acid (I-78a: 6.4 gm, 38.5 mmol) in methanol (100 mL) was reduced with 10% Pd/C (640 mg) to afford the crude product, 5 g (80.69% yield).
출처 및 근거
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| 특허 번호 | US08946260B2 |
| 출처 데이터셋 | uspto-grants-2015_02 |
| ORD ID | ord-7a510fce0be64052bf67aa17848ce7a5 |
| 출처 메모 | uspto-grants-2015_02 |