Tetrahydrofuran → 3-(3-Bromo-thieno[2,3-b]pyridin-2-yl)-8-(1-ethyl-propyl)-2,6-dimethyl-imidazo[1,2-b]pyridazine

HRID 184411

반응식

[Br:1][c:2]1[cH:3][s:4][c:5]2[n:6][cH:7][cH:8][cH:9][c:10]12.[CH2:11]([Li:12])[CH2:13][CH2:14][CH3:15].[CH2:16]([CH3:17])[CH:18]([CH2:19][CH3:20])[c:21]1[c:22]2[n:23]([n:24][c:25]([CH3:27])[cH:26]1)[c:28]([I:32])[c:29]([CH3:31])[n:30]2.[CH2:33]1[O:34][CH2:35][CH2:36][CH2:37]1.[CH3:38][CH2:39][CH2:40][CH2:41][CH2:42][CH3:43]>>[Br:1][c:2]1[c:3](-[c:28]2[n:23]3[c:22]([c:21]([CH:18]([CH2:16][CH3:17])[CH2:19][CH3:20])[cH:26][c:25]([CH3:27])[n:24]3)[n:30][c:29]2[CH3:31])[s:4][c:5]2[n:6][cH:7][cH:8][cH:9][c:10]12