4-Chlorophenol → 3-(4-Chlorophenoxy)propan-1-amine

HRID 1844405

반응식

HRID 1844405 반응식
Cl[C:2]1[CH:12]=[CH:11][CH:10]=[C:9](Cl)[C:3]=1[O:4][CH2:5][CH2:6][CH2:7][NH2:8].[Cl:14]C1C=CC=C(Cl)C=1O.ClC1C=CC(O)=CC=1>>[Cl:14][C:11]1[CH:10]=[CH:9][C:3]([O:4][CH2:5][CH2:6][CH2:7][NH2:8])=[CH:2][CH:12]=1

참가 물질

4

반응물 3

HCID 46844-ChlorophenolHCID 68992,6-DichlorophenolHCID 33042863-(2,6-Dichlorophenoxy)propan-1-amine

생성물 1

HCID 64846543-(4-Chlorophenoxy)propan-1-amine수율 85%

실험 절차

Intermediate 11 (150 mg, 0.808 mmol, 85% yield) was prepared as a white powder following the procedure described for Intermediate 9 replacing 2,6-dichlorophenol with 4-chlorophenol as starting material. LC-MS (ESI) 186 (M+H), RT=1.41 min (Method B).

출처 및 근거

ORD 기록
ord-b8e99765dcef43beb74ddbd54c20503d
출처 데이터셋
uspto-grants-2015_02
특허 번호
US08946430B2

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