Methoxyacetic Acid → 2-(methoxymethyl)-4-methyl-1H-benzo[d]imidazol-6-ol

반응식

[NH2:1][C:2]1[CH:3]=[C:4]([OH:10])[CH:5]=[C:6]([CH3:9])[C:7]=1[NH2:8].[CH3:11][O:12][CH2:13][C:14](O)=O>>[CH3:11][O:12][CH2:13][C:14]1[NH:1][C:2]2[CH:3]=[C:4]([OH:10])[CH:5]=[C:6]([CH3:9])[C:7]=2[N:8]=1

참가 물질

반응물 2

HCID 12251Methoxyacetic Acid

HCID 199076443,4-Diamino-5-methylphenol

생성물 1

HCID 669782392-(methoxymethyl)-4-methyl-1H-benzo[d]imidazol-6-ol

실험 절차

0.55 g (4.00 mmol) 3,4-diamino-5-methyl-phenol and 1.57 mL (20.00 mmol) methoxy-acetic acid were stirred for 1 h at 120° C. Then the reaction mixture was evaporated down and further reacted as crude product.

후처리

customThen the reaction mixture was evaporated down
customfurther reacted as crude product

출처 및 근거

ORD 기록: ord-0a9782ae3d6c474b9a96289133f1de66
출처 데이터셋: uspto-grants-2015_02
DOI: 10.6084/m9.figshare.5104873.v1
특허 번호: US08952014B2

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