4-Amino-3-methyl-5-nitrophenol → 3,4-Diamino-5-methylphenol

HRID 1846488노트

반응식

HRID 1846488 반응식
[NH2:1][C:2]1[C:7]([N+:8]([O-])=O)=[CH:6][C:5]([OH:11])=[CH:4][C:3]=1[CH3:12].[H][H]>CO.[Pd]>[NH2:8][C:7]1[CH:6]=[C:5]([OH:11])[CH:4]=[C:3]([CH3:12])[C:2]=1[NH2:1]

참가 물질

5

반응물 2

HCID 669782964-Amino-3-methyl-5-nitrophenolHCID 178418361HCID 178418361, 화합물2회

생성물 1

HCID 199076443,4-Diamino-5-methylphenol

시약·촉매·용매 2

HCID 23938Palladium촉매HCID 887Methanol용매

실험 절차

2.00 g (11.06 mmol) 4-amino-3-methyl-5-nitrophenol were placed in 50 mL methanol and hydrogenated under a hydrogen atmosphere and with the addition of 1.00 g Pd/C (10%) at 50° C. and a hydrogen pressure of 5 bar until all the hydrogen had been taken up. The catalyst was filtered off and the filtrate was evaporated down i.vac.

후처리

  1. filtrationThe catalyst was filtered off
  2. customthe filtrate was evaporated down i.vac

출처 및 근거

ORD 기록
ord-df0ec7a994e64585a5891541074e1775
출처 데이터셋
uspto-grants-2015_02
특허 번호
US08952014B2

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