Potassium Carbonate → HCID 178478257, 화합물
반응식
[Cl:1][C:2]1[C:7]2[NH:8][C:9]([CH:11]3[CH2:15][CH2:14][O:13][CH2:12]3)=[N:10][C:6]=2[CH:5]=[C:4]([OH:16])[CH:3]=1.[Cl:17][C:18]1[CH:23]=[C:22](Cl)[N:21]=[CH:20][N:19]=1.C(=O)([O-])[O-].[K+].[K+]>CN(C=O)C>[Cl:1][C:2]1[C:7]2[NH:8][C:9]([CH:11]3[CH2:15][CH2:14][O:13][CH2:12]3)=[N:10][C:6]=2[CH:5]=[C:4]([O:16][C:22]2[CH:23]=[C:18]([Cl:17])[N:19]=[CH:20][N:21]=2)[CH:3]=1참가 물질
5
실험 절차
80 mg (0.34 mmol) 7-chloro-2-(tetrahydrofuran-3-yl)-1H-benzo[d]imidazol-5-ol and 51 mg (0.34 mmol) 4,6-dichloropyrimidine were placed in 2.0 mL DMF. 55 mg (0.40 mmol) potassium carbonate were added and the mixture was stirred overnight at RT. The reaction mixture was filtered and purified by chromatography. The fractions containing product were combined and evaporated down i.vac.