3-(2-Methyl-thiazol-4-yl)-phenylamine → 2-((1R,2S)-2-aminocyclohexylamino)-4-(3-(2-methylthiazol-4-yl)phenylamino)pyrimidine-5-carboxamide

HRID 1846714

반응식

HRID 1846714 반응식
[NH2:1][C@H:2]1[CH2:7][CH2:6][CH2:5][CH2:4][C@H:3]1[NH:8][C:9]1[N:14]=[C:13](NC2C=CC(C3ON=CC=3)=CC=2)[C:12]([C:27]([NH2:29])=[O:28])=[CH:11][N:10]=1.[CH3:30][C:31]1[S:32][CH:33]=[C:34]([C:36]2[CH:37]=[C:38]([CH:40]=[CH:41][CH:42]=2)[NH2:39])[N:35]=1>>[NH2:1][C@H:2]1[CH2:7][CH2:6][CH2:5][CH2:4][C@H:3]1[NH:8][C:9]1[N:14]=[C:13]([NH:39][C:38]2[CH:40]=[CH:41][CH:42]=[C:36]([C:34]3[N:35]=[C:31]([CH3:30])[S:32][CH:33]=3)[CH:37]=2)[C:12]([C:27]([NH2:29])=[O:28])=[CH:11][N:10]=1

참가 물질

3

반응물 2

HCID 7365353-(2-Methyl-thiazol-4-yl)-phenylamineHCID 461846122-[[(1R,2S)-2-aminocyclohexyl]amino]-4-[4-(1,2-oxazol-5-yl)anilino]pyrimidine-5-carboxamide

생성물 1

HCID 461843682-((1R,2S)-2-aminocyclohexylamino)-4-(3-(2-methylthiazol-4-yl)phenylamino)pyrimidine-5-carboxamide

실험 절차

This compound was synthesised using the synthetic scheme described for the synthesis of compound 122, and using 3-(2-methylthiazol-4-yl)aniline in step 1. MS: 424.37 (M+H).

후처리

  1. customThis compound was synthesised

출처 및 근거

ORD 기록
ord-710548bb7e83451193cecbd2faefa72a
출처 데이터셋
uspto-grants-2015_02
특허 번호
US08952027B2

연결된 노트

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