Huagongshe화공사 화학 정보 인쇄 보고서 · 연구 참고용
Trifluoroacetic acid → Trifluoroacetic acid
참여 물질
| 역할 | 이름 | HCID | 투입량 |
|---|---|---|---|
| 반응물 | Trifluoroacetic acid | HCID 6422 | — |
| 반응물 | 2-(Boc-amino)-4-methylthiophene | HCID 57471983 | — |
| 용매 | Dichloromethane | HCID 6344 | — |
| 생성물 | Trifluoroacetic acid | HCID 6422 | — |
| 생성물 | 4-Methylthiophen-2-amine | HCID 12231192 | — |
반응 단계
A solution of tert-butyl 4-methylthiophen-2-ylcarbamate (0.880 g, 4.13 mmol) in CH2Cl2 (8 mL) and TFA (6 mL) wad stirred at room temperature for 3 h. Solvents was removed in vacuo to give 4-methylthiophen-2-amine as trifluoroacetic acid salt (0.920 g).
출처 및 근거
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| 특허 번호 | US08952027B2 |
| 출처 데이터셋 | uspto-grants-2015_02 |
| ORD ID | ord-5af6f8ec47ba49238569a926d5c0d60f |
| 출처 메모 | uspto-grants-2015_02 |