Nitric Acid → Norvaline Dinitrate

HRID 1846920노트

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HRID 1846920 반응식
[N+:1]([O-:4])([OH:3])=[O:2].[NH2:5][C@H:6]([C:10]([OH:12])=[O:11])[CH2:7][CH2:8][CH3:9].[N+:13]([O-:16])([OH:15])=[O:14].[NH2:17][C@H:18]([C:22]([OH:24])=[O:23])[CH2:19][CH2:20][CH3:21]>O>[N+:1]([O-:4])([OH:3])=[O:2].[N+:13]([O-:16])([OH:15])=[O:14].[NH2:5][C@H:6]([C:10]([OH:12])=[O:11])[CH2:7][CH2:8][CH3:9].[N+:1]([O-:4])([OH:3])=[O:2].[N+:1]([O-:4])([OH:3])=[O:2].[N+:1]([O-:4])([OH:3])=[O:2].[NH2:17][C@H:18]([C:22]([OH:24])=[O:23])[CH2:19][CH2:20][CH3:21]

참가 물질

6

반응물 3

HCID 944Nitric AcidHCID 65098L-NorvalineHCID 86628854HCID 86628854, 화합물

생성물 2

HCID 86628852Norvaline DinitrateHCID 86628853Norvaline Trinitrate

시약·촉매·용매 1

HCID 962Water용매

실험 절차

Applicants have cost-effectively synthesized Norvaline Nitrate by combining nitric acid and Norvaline, mixing with water, and leaving to crystallize. Further nitratization can take place, yielding Norvaline Dinitrate or Norvaline Trinitrate. An alternative implementation comprises substituting Nitrous Acid (HNO2) for Nitric Acid (HNO3), thus yielding Norvaline Nitrite. Norvaline Nitrite has the same effects as Norvaline Nitrate, the only difference being that it requires one less step to yield Nitric Oxide (NO—). Mixed salts may also be used, such as in the non-limiting example of Norvaline Nitrate-Orotate.

후처리

  1. customleaving
  2. customto crystallize

출처 및 근거

ORD 기록
ord-f09385c8fafd476ead94ac0e1e2dfcba
출처 데이터셋
uspto-grants-2015_02
특허 번호
US08952047B1

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