Huagongshe화공사 화학 정보 인쇄 보고서 · 연구 참고용
Benzenemethanamine, 3,4-dichloro- → 3-[(3,4-Dichlorobenzyl)amino]pyridine-4-carboxylic acid
참여 물질
| 역할 | 이름 | HCID | 투입량 |
|---|---|---|---|
| 반응물 | Benzenemethanamine, 3,4-dichloro- | HCID 1608 | — |
| 반응물 | 3-Fluoropyridine-4-carboxylic acid | HCID 345361 | — |
| 생성물 | 3-[(3,4-Dichlorobenzyl)amino]pyridine-4-carboxylic acid | HCID 86728201 | 37% |
반응 단계
The title compound was prepared in 37% yield from 3,4-dichlorobenzylamine and 3-fluoroisonicotinic acid according to the procedure for the preparation of Example 3. 1H NMR (400 MHz, DMSO-d6): δ 13.48 (br s, 1H), 8.10 (s, 1H), 7.84 (d, 1H, J=5.0 Hz), 7.57-7.65 (m, 3H), 7.35 (dd, 1H, J=8.3, 1.9 Hz), 4.59 (s, 2H). [M+H] calc'd for C13H10Cl2N2O2, 297, 299. Found 297, 299.
출처 및 근거
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| 특허 번호 | US08952151B2 |
| 출처 데이터셋 | uspto-grants-2015_02 |
| ORD ID | ord-168edbd905ca4ea39e03b3f553172ef7 |
| 출처 메모 | uspto-grants-2015_02 |