2-(Benzyloxy)-5-(methoxymethoxy)pyridine → HCID 178498305, 화합물
반응식
C([O:8][C:9]1[CH:14]=[CH:13][C:12]([O:15][CH2:16][O:17][CH3:18])=[CH:11][N:10]=1)C1C=CC=CC=1>CCO.[Pd]>[CH3:18][O:17][CH2:16][O:15][C:12]1[CH:13]=[CH:14][C:9]([OH:8])=[N:10][CH:11]=1참가 물질
4
실험 절차
To 2-(benzyloxy)-5-(methoxymethoxy)pyridine (1.8 g, 8.71 mol) in EtOH was added Pd/C (1.0 g). The mixture was charged with H2 (15 psi), stirred at RT for 45 min, filtered, and concentrated to give 5-(methoxymethoxy)pyridin-2-ol (1.35 g, quantitative yield) as a pale yellow solid. MS (ESI) m/z 156.1 [M+H]+.
후처리
- additionThe mixture was charged with H2 (15 psi)
- filtrationfiltered
- concentrationconcentrated
출처 및 근거
- ORD 기록
- ord-6b5a56b88a2f41c19ffcfd2f83eb1f18
- 출처 데이터셋
- uspto-grants-2015_02
- 특허 번호
- US08952171B2
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