3-Methyl-2-(5-oxo-2,5-dihydrofuran-3-yl)-2,8-diazaspiro[4.5]decan-1-one → 3-Ethyl-2-(5-oxo-2,5-dihydrofuran-3-yl)-2,8-diazaspiro[4.5]decan-1-one
반응식
[CH2:1]([CH:3]1[CH2:7][C:6]2([CH2:12][CH2:11][N:10](C(OC(C)(C)C)=O)[CH2:9][CH2:8]2)[C:5](=[O:20])[NH:4]1)[CH3:2].CC1CC2(CCNCC2)C(=O)N1[C:33]1[CH2:34][O:35][C:36](=[O:38])[CH:37]=1>>[CH2:1]([CH:3]1[CH2:7][C:6]2([CH2:8][CH2:9][NH:10][CH2:11][CH2:12]2)[C:5](=[O:20])[N:4]1[C:33]1[CH2:34][O:35][C:36](=[O:38])[CH:37]=1)[CH3:2]참가 물질
3
실험 절차
The title compound was prepared in two steps from tert-butyl 3-ethyl-1-oxo-2,8-diazaspiro[4.5]decane-8-carboxylate in an analogous fashion as described for 3-methyl-2-(5-oxo-2,5-dihydrofuran-3-yl)-2,8-diazaspiro[4.5]decan-1-one (I-22).
출처 및 근거
- ORD 기록
- ord-27556186f0fa4ad5bc7e62e4113026a4
- 출처 데이터셋
- uspto-grants-2015_02
- 특허 번호
- US08952166B2
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