3-Ethyl-2-(5-oxo-2,5-dihydrofuran-3-yl)-2,8-diazaspiro[4.5]decan-1-one → 3-Cyclopropyl-2-(5-oxo-2,5-dihydrofuran-3-yl)-2,8-diazaspiro[4.5]decan-1-one
반응식
[CH:1]1([C:4](=C)[CH2:5][C:6]2([C:19]([O:21]CC)=O)[CH2:11][CH2:10][N:9](C(OC(C)(C)C)=O)[CH2:8][CH2:7]2)[CH2:3][CH2:2]1.C(C1CC2(CCNCC2)C(=O)[N:28]1[C:38]1[CH2:39][O:40][C:41](=[O:43])[CH:42]=1)C>>[CH:1]1([CH:4]2[CH2:5][C:6]3([CH2:7][CH2:8][NH:9][CH2:10][CH2:11]3)[C:19](=[O:21])[N:28]2[C:38]2[CH2:39][O:40][C:41](=[O:43])[CH:42]=2)[CH2:2][CH2:3]1참가 물질
3
실험 절차
The title compound was prepared from 1-tert-butyl 4-ethyl 4-(2-cyclopropylallyl)piperidine-1,4-dicarboxylate in four steps in an analogous fashion as described for 3-ethyl-2-(5-oxo-2,5-dihydrofuran-3-yl)-2,8-diazaspiro[4.5]decan-1-one (I-43).
출처 및 근거
- ORD 기록
- ord-aa3edea55ad74c7da57cbd0179d04996
- 출처 데이터셋
- uspto-grants-2015_02
- DOI