3,5-Diamino-1,2,4-triazole → HCID 178508251, 화합물

HRID 1851217

반응식

HRID 1851217 반응식
[NH2:1][C:2]1[N:6]=[C:5]([NH2:7])[NH:4][N:3]=1.[C:8]1([CH:14]([C:20](OCC)=[O:21])[C:15](OCC)=[O:16])[CH:13]=[CH:12][CH:11]=[CH:10][CH:9]=1>C(N(CCCC)CCCC)CCC>[NH2:1][C:2]1[N:6]=[C:5]2[N:7]=[C:15]([OH:16])[C:14]([C:8]3[CH:13]=[CH:12][CH:11]=[CH:10][CH:9]=3)=[C:20]([OH:21])[N:4]2[N:3]=1

참가 물질

4

반응물 2

HCID 150783,5-Diamino-1,2,4-triazoleHCID 66514Diethyl phenylmalonate

생성물 1

HCID 178508251HCID 178508251, 화합물

시약·촉매·용매 1

HCID 7622Tributylamine용매

실험 절차

A solution of 9.0 g 3,5-diamino-1,2,4-triazole and 22.4 mL diethyl phenylmalonate in N,N-dibutylbutan-1-amine was heated under microwave irradiation to 180° C. for 8 h. The reaction mixture formed two layers after cooling to room temperature. The top layer was removed and the solvent of the lower layer was evaporated. The residue was treated with water and acidified with 5N HCl. The precipitated product was collected by filtration and dried. The crude product was used without further purification.

후처리

  1. customThe reaction mixture formed two layers
  2. customThe top layer was removed
  3. customthe solvent of the lower layer was evaporated
  4. additionThe residue was treated with water
  5. filtrationThe precipitated product was collected by filtration
  6. customdried
  7. customThe crude product was used without further purification

출처 및 근거

ORD 기록
ord-66d812d7ed2d46ae9b8c90c93a1783d1
출처 데이터셋
uspto-grants-2015_02
특허 번호
US08957064B2

연결된 노트

불러오는 중…