HCID 178498471, 화합물 → Methyl 5-amino-1H-pyrazole-3-carboxylate

HRID 1851230노트

반응식

HRID 1851230 반응식
[N+:1]([C:4]1[CH:8]=[C:7]([C:9]([O:11][CH3:12])=[O:10])[NH:6][N:5]=1)([O-])=O>CO.[Pd]>[NH2:1][C:4]1[CH:8]=[C:7]([C:9]([O:11][CH3:12])=[O:10])[NH:6][N:5]=1

참가 물질

4

반응물 1

HCID 178498471HCID 178498471, 화합물

생성물 1

HCID 18445864Methyl 5-amino-1H-pyrazole-3-carboxylate

시약·촉매·용매 2

HCID 23938Palladium촉매HCID 887Methanol용매

실험 절차

To 14.0 g methyl 3-nitro-1H-pyrazole-5-carboxylate in 200 mL methanol were added 1.2 g Pd/C (10% w/w). The mixture was stirred under H2-atmosphere at room temperature for 18 h. The mixture was filtered through Celite. The filtrate was concentrated and the crude product was used without further purification.

후처리

  1. filtrationThe mixture was filtered through Celite
  2. concentrationThe filtrate was concentrated
  3. customthe crude product was used without further purification

출처 및 근거

ORD 기록
ord-81fc562003f548ffa06cdd3904f5e467
출처 데이터셋
uspto-grants-2015_02
특허 번호
US08957064B2

반응 노트

불러오는 중…